A Major Advance in Live-Carrier Vaccines

A comparative study of two live measles vaccines in Iran

a comparative study of two live measles vaccines in iran

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A Major Advance in Plastid Transformation.

In this issue of Plant Physiology, Pal Maliga’s laboratory reported a major advance in plastid transformation. Stable manipulation of the plastid genome of flowering plants was first reported nearly 30 years ago (Svab et al., 1990). The approach was to select transplastomic plants using spectinomycin, which blocks translation by the prokaryotic-type 70S ribosomes found in plastids. Thus, in the...

Carrier molecules for use in veterinary vaccines.

The practice of immunization of animals and humans has been carried out for centuries and is generally accepted as the most cost effective and sustainable method of infectious disease control. Over the past 20 years there have been significant changes in our ability to produce antigens by conventional extraction and purification, recombinant DNA and synthesis. However, many of these products ne...

Actinobacillus pleuropneumoniae for Use in Live Vaccines

Clonal, noniridescent mutants ofActinobaciUlus pleuropneumoniae serotypes 1 and 5 were isolated following chemical mutagenesis with ethyl methanesulfonate. The absence of any detectable capsule was confirmed by inhibition radioimmunoassay. There were no differences between the parent and mutant strains in lipopolysaccharide or protein electrophoretic profiles or in hemolytic activity. There was...